Drug Induced Constipation

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Listed below are some drugs that may cause constipation

  • Aluminium containing antacids
  • Calcium containing antacids
  • Antispasmodics e.g. mebeverine, peppermint oil
  • Antimuscarinics e.g. atropine, dicycloverine, hyoscine butylbromide, hyoscine hydrobromide, procyclidine, oxybutynin, darifenacin, flavoxate, tolerodine
  • Bile acid sequestrants: colestyramine, colesevelam, colestipol
  • Diuretics e.g. furosemide
  • Sedating antihistamines e.g. chlorphenamine, promethazine
  • Opioid analgesics e.g. codeine, dihydrocodeine, morphine, tramadol
  • Tricyclic antidepressants e.g. amitriptyline, dosulepin, imipramine
  • Monoamine-oxidase inhibitors (MAOIs) e.g. moclobemide, phenelzine
  • Antipsychotics e.g. amisulpride, chlorpromazine, quetiapine, clozapine
  • Antiparkinson drugs e.g. entacapone, pramipexole, procyclidine, selegiline, orphenadrine
  • Antiepileptic drugs e.g. carbamazepine, oxcarbazepine, phenytoin, pregabalin
  • Clonidine
  • Methyldopa
  • Alpha blockers e.g. prazosin, tamsulosin, doxazosin
  • Calcium channel blockers: diltiazem, verapamil
  • Iron preparations
  • Calcium supplements
  • Bisphosphonates e.g. alendronic acid, risedronate
  • Bupropion
  • Sucralfate
  • Fidaxomicin
  • Baclofen

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